Chemocoxib A

Research use only, not for human use.

Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively.

Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively; shows no signigicant activity against COX-1, and COX-2 mutant V349L, V523I, and S530A; exhibits cytotoxicity in cancer cell culture, inhibits the growth of human tumor xenografts in nude mice.

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Chromatin/Epigenetic

COX

COX

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960214-84-0

924.397

C49H50ClN3O13

>98% (HPLC)

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Butanoic acid, 4-[[4-[[2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]butyl]amino]-4-oxo-, (5R,5aR,8aR,9R)-5,5a,6,8,8a,9-hexahydro-8-oxo-9-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-5-yl ester

(-20℃)

With Ice Pack

≥ 2 years